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Dream of Oxidative spotlight Hydroxyacetanilide patterns of protein adduction, 103 difficulty representing covalent binding theory, 102 Hydroxyethyl radicals, 266 Hydroxynonenal contribution to alky steatosis in mice, 273 shape during alcohol intoxication, 266 creation during lipid peroxidation, 111 Hypersensitivity toxicity, function of vaccinated mechanisms, 43 Hypothesis-free fact-finding, enabled by omics technology, 119 I Idiosyncratic toxicity, ALDH2 polymorphisms and john barleycorn warmth, 41 Immune structure complement pathway involvement in tippler liver disease, 270 complex roles in carcinoma increase, 227 impersonation in drinker liver infection, 270 lines in asbestosis, 254 responsibility in paracetamol hepatoxicity (innate), 165 situation of adaptive exempt rejoinder in alcohol toxicity, 271 Inositol requiring enzyme-1 (IRE1) activation pathway, 145 duty in ER bring into prominence response, 145 Intercontinental Agency proper for Study on Cancer (IARC) association of non-lung cancer wiuth smoking, 294 carcinogen classification methodology, 246 Interstitial nephritis, 179 Isoprostanes, biomarkers of lipid peroxidation, 111 Isotretinoin, 199 J Jaundice, hyperbilirubinemia in problem drinker liver sickness, 274 K Keap1, 141 Kidney(s) underlying structure and functions, 176 factors predisposing to toxicity, 176 abuse via trichloroethylene, 184 role in xenobiotic excretion, 83 Kidney harm marker-1 (KIM-1) urinary marker of kidney expense, 180 handle in trichlorethylene users, 185 Kupffer cells prime features, 158 character in intoxicating liver disease, 270 L Inveigle, 9 mien in tobacco smoke, 298 Legislative initiatives Chemical Substances Check Law (Japan), 19 Index The using software is effort version. 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